Abstract. The Bern medical cyclotron laboratory is based on a 18 MeV proton cyclotron equipped with a specifically conceived 6 m long research beam line, terminated in a separate bunker. This particular configuration is designed for industrial Positron Emission Tomography (PET) radioisotope production as well as for novel detector, radiation biophysics, radiation protection, materials science, radiochemistry and radiopharmacy scientific activities. In particular, radiation hardness studies for space missions and high- energy physics experiments are performed. This project is the result of the successful collaboration among the University Hospital in Bern (Inselspital), the University of Bern and industrial partners. This facility is open to national and international collaborations. The scientific results of the first five years of operation will be presented.

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